Abstract:
Both biochemical and mechanical factors have to be taken into account if a meaningful model for the formation, growth, and lysis of clots in flowing blood is to be developed. Most models that are currently in use neglect one or the other of these factors. A model believe that incorporates many of the crucial biochemical and rheological factors that play a role in the formation, growth, and lysis of clots will be presented within the context of a general thermodynamic framework that has been able to explain a plethora of disparate phenomena. General issues with respect to the mathematical modeling of thrombus formation and lysis, as well as interesting computational challenges that the model presents, will be discussed.
This seminar is easily accessible to persons with disabilities. For more information or for assistance, please contact the Mathematics Department at 743-3500.