< Aneurysms and Stents >

"Aortic aneurysm" in the encyclopedia

Aneurysm is characterized by the formation of sac-like protrusions of weakened sections of blood vessels that can rupture and be fatal. There is a 90% mortality rate associated with an out-of-hospital AAA rapture. Until recently, surgery has been the only treatment to prevent the aneurysm from rupturing. Since most of the patients are 55 or older and high risk, undergoing general anesthesia is not a solution.

Within the past ten years an innovative non-invasive procedure, which requires only local anesthesia, has been developed. The new procedure entails inserting a catheter (a hollow tube) into an artery and directing it to the site of the aneurysm. Placed in the catheter is a spring-like device called a stent, see Figure 1, which serves to hold open the weakened artery and to exclude the aneurysm from circulation. This lowers the probability of rupture and promotes aneurysm shrinking due to thrombosis caused by the lack of blood supply to the aneurysm tissue.

A sketch of a stent and of a stented aneurysm
A sketch of a stent and of a stented aneurysm

The procedure is still considered experimental and reports of mid- or long-term outcomes indicate structural and positional changes of the stent, including buckling, kinking and migration. To improve the procedure, optimal stent design depending on the patients anatomy and a study of the optimal anchoring strategies are needed. These are the objectives of our study.

The movies below show the pulsation of the stented abdominal aorta (without the aneurysmal pouch) over one cardiac cycle. Also shown is the radius change axial and circumferrential strain and the transmurral pressure.

Length of the vessel shown: 10cm (0.1m)
Stent anchoring sites: x = 0.015m (proximal) x = 0.085m (distal)

Collaborators:

Dr. Zvonimir Krajcer, MD. F.A.C.C. Interventional Cardiologist Clinical Associate Professor in Medicine Baylor College of Medicine and the University of Texas Health Science Center Texas Heart Institute & St. Luke's Episcopal Hospital

Dr. K. Ravi-Chandar, Professor University of Texas in Austin Center for Mechanics of Solids, Structures and Materials