< Texas Heart Institute Experiments >
performed at the
THI Cardiovascular Research Laboraroty of Dr. Doreen Rosenstrauch, M.D.

Joy Chavez (Undergraduate Student at UH)
Dr. Craig Hartley (Baylor College of Medicine)
Dr. Doreen Rosenstrauch (Texas Heart Insitute)
Hassan Khalil (Undergraduate Student at UH)
Prof. Suncica Canic (UH)
The following pictures and movies show the experimental setup and some results obtained from our Mock Circulatory Flow Loop built at the Texas Heart Institute by the above mentioned patricipants. The flow loop uses a Left Ventricular Assist Device (LVAD; purchased using Roderick Duncan MacDonald Research grant awarded by St. Luke's Episcopal Hospital) as a pulsatile flow pump generating physiologically reasonable pressure waves, and a custom-made latex tubing (donated by Kent Elastomer Inc.) as an elastic flow conduit. Ultrasound measurements of wall motion and of the flow velocity were performed by Dr. Hartley, whose expertise is in cardiovascular ultrasound measurements and instrumentation. Excellent agreement between the experiment and numerical simulations of the reduced Biot system was obtained.

Research plan:

  • Validation of a mathematical model for fluid-structure interaction between a viscous incompressible Newtonian fluid and an elastic structure;
  • Validation of a mathematical model for fluid-structure interaction with an inserted vascular prosthesis (AneuRx Stent-Graft; donated by Medtronic Inc.)
  • Derivation of new models for viscoelastic behavior of vessel walls coupled with the time-dependent flow of a viscous incompressible Newtonian fluid
  • Testing a viable human aorta with and without the inserted prosthesis

    Click on picture to enlarge or run a movie.

    HeartMateDrive consolePump implantation
    Display of parametersJoy and the setup

    Movie showing tube pulsatility (QuickTime)