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> Putnam Math Competition
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Print
Announcement
Matthew Bennett
Rice University, Dept. of Biosciences
The mathematics of synthetic biology: A quantitative perspective
on engineering biological complexity
March 24, 2016
4:00 pm PGH
646
Abstract
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Synthetic biology is the engineering and construction of novel cellular
systems through genetic manipulation. However, the complex interactions
between genes, proteins, metabolites, and cells form intricate networks
that are difficult to understand in the absence of mathematical modeling.
In this talk, I will discuss my lab's work to understand, both
theoretically and experimentally, the basic principles underlying synthetic
gene circuits. These investigations have led us to a better understanding
of the impact that nonlinearity, stochasticity, and delay have on the
dynamics of gene networks. Further, we have used these principles to design
bigger and more complicated synthetic systems that span large populations
of different bacterial cells types. These systems, called synthetic
microbial consortia, are among the most complex forms of synthetic life and
their behaviors strain our ability to accurately model their dynamics. I
will describe our recent efforts to effectively model these multi-scale
spatiotemporal systems and outline the current challenges in the field.
Pizza will be served.
Click for announcement to post
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