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Branching Dendrites with Resonant Membrane: Asum-over-trips approach

S. Coombes, Y. Timofeeva, C.-M. Svensson, G.J. Lord, K. Josic, S.J. Cox and C.M. Colbert.

Dendrites are complex branching structures that receive and process thousands of synaptic inputs from other neurons. It is well known that dendritic morphology plays an important role in the function of dendrites. Another important contribution to the response characteristics of a single neuron comes from the intrinsic resonant properties of dendritic membrane. In this paper we combine the effects of dendritic branching and resonant membrane dynamics by generalising the âœsumover- trips❠approach (Abbott et al. in Biol Cybernetics 66, 49â“60 1991). To illustrate how this formalism can shed light on the role of architecture and resonances in determining neuronal output we consider dual recording and reconstruction data from a ratCA1 hippocampal pyramidal cell.

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